Medicinal plants being the effective source ofrnboth traditional and modern medicines, are genuinely useful for primary healthrncare. Lantana camara and Solanum elaeagnifolium were pharmacologicallyrnevaluated. Phytochemical screening of ethanol and petroleum ether extractsrnclearly showed the presence of certain important secondary metabolites. Amongrnthe two extracts, the ethanol extract was found to be more potent thanrnpetroleum ether extract. The antioxidant activity of the plant extracts wererndetermined by using Phospho – molybdenum assay, Nitric oxide free radicalrnscavenging assay and FRAP assay. The results of the present study clearlyrnindicated that Ethanol extract showed better Nitric oxide free radicalrnscavenging activity in S. elaeagnifolium at concentration of 1000 mg/mlrnof extract. Among the two plant material, the S. elaeagnifolium wasrnfound to be more potential than the L. camara.