An ethnomedicinal studies was conducted in the Hathras district of Uttar Pradesh. The important information on the medicinal plants was obtained from the traditional medicinal peoples. Present investigations were carried out for the evaluation on the current status and survey on these medicinal plants. In the study we present 14 species of medicinal plants which are commonly used among the peoples of Hathras district (U.P.) to cure diabetes and jaundice diseases. This study is important to preserve the knowledge of medicinal plants used by the rural and tribal peoples of Hathras district (U.P.), the survey of psychopharmacological and literature of these medicinal plants have great pharmacological and ethnomedicinal significance.