Coriandrum sativum L. (Dhania) is one of the earliest spices known to mankind. It is grown in fields for green leaves and dry fruits. Coriander suffers severely from stem gall disease caused by the fungus Protomyces macrosporus. Present study deals with the changes in total protein contents of healthy and diseased tissues of coriander both in vivo and in vitro. Total protein contents were estimated following the method of Lowry et al. (1951). Galled tissues of coriander showed high protein contents as compared to their normal counterparts both in vivo and in vitro.