Ethnobotanical science is an interdisciplinary science, which is a combination of anthropology, human health, animal health and botany. It also needs the collaborations of other disciplines like chemistry and pharmacology. The important work of botanists is to entirely rely on, to identify accurately the plants used by tribals and study their ecology and environment in which it is growing. Keeping this in a view the present work on North-Eastern Karnataka which comprises Bellary, Raichur, and Gulbarga and Bidar districts, are considered for the present ethnobotanical study.