The Flora of Pakistan having a huge diversity in medicinal plants due to climatic, topographic, physiographic, altitudinal and edaphic conditions. The present study focus upon the Ficus carica to analyze its quantitative, qualitative, biological, pharmacological, phytochemical analysis and antioxidant properties of methanolic extract from leaves. The present exhaustive work revealed that Ficus carica has potential source of therapeutic agents in domestic health care practices and a significant source for development. The leaves of both wild and cultivated showed antibacterial activities and clear zone of inhibition in the methanol extracts. The comparative analysis showed that leaves of wild plant exhibits greater antibacterial activity against Bacillus sabtilis followed by Kleisbella pnumoniae.