The study investigated the phytochemical constituents of leaf and root bark of Calotropis procera and Parquetna nigrescens. This was with a view to determining quantitatively the phytochemical constituents of leaf and root bark of C. procera and P. nigrescens for their potential use as bio-insecticide of insect pests. Total phenolic, flavonoid, condensed tannins, alkaloid and saponin content of leaf and root bark of C. procera and P. nigrescens were quantified. The quantity of saponin and alkaloid were the highest, followed by phenol while the least contents were the condensed tannins and flavonoid. The highest alkaloid content (60.40±0.02 mg/g) was in the ethanolic extract of P. nigrescens leaf, followed by methanolic extract of P. nigrescens leaf (39.50±0.01 mg/g) and the lowest alkaloid content of 16.50±0.02 mg/g was recorded with methanolic extract of P. nigrescens root bark.