Materials and Methods: Fresh fruits of Dhanyaka (C. sativum Linn.) were collected from Rona, Gadag district and authenticated. Few fruits were stored in an air tight containers for one year. Both samples were subjected for macro-microscopic and powder microscopic studiesas per the standard methodology.

Results and Discussion: Macroscopically fresh fruits were globular, covered with ridges, dry schizocarp. Old sample showed secondary ridges but were not very prominent. Fresh sample was slightly sweet, more aromatic, ridged and intact compared to that of old sample which was mild aromatic and easily broken. Microscopic findings of fresh sample were the presence of secondary ridges with intact epicarp. The endocarp was paraquetry in arrangement. Vascular bundle was crowning the sclerenchyma region. Significant changes observed among old sample (S2) was worn out epicarp and imperceptible endocarp. Vascular bundle was not prominent in this sample. Powder microscopy showed presence of a greater number of oil globules and aleurone granules in fresh sample.

Conclusion: The macro-microscopy, powder microscopic studies done for both fresh and old sample of Dhanyaka (Coriandrum sativum Linn.) showed few structural changes signifying the effect of drug collection, preservation.