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International Journal of
Botany Studies
ARCHIVES
VOL. 5, ISSUE 3 (2020)
in silico molecular docking reveals the interaction of coumarin with the Sars-Cov-2 main protease
Authors
Ruplin Nayak, Shraban Kumar Sahoo, Pradip Kumar Prusty, Gagan Kumar Panigrahi
Abstract
2019 Novel corona-virus (2019-nCoV) has put the entire globe into unrest. Unavailability of specific drug against the virus is more imperative. This challenging situation requires development of bio-molecules for efficient treatment against severe acute 2019-nCoV. The crystal structure of SARS-CoV-2 main protease (Mpro) is known and may be used for fast In silico molecular docking. This may result into identification of active biomolecules primarily phytochemical. In silico Molecular Docking revealed that the phytochemical, coumarin effectively binds at the active pocket of the SARS-CoV-2 main protease.
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Pages:440-442
How to cite this article:
Ruplin Nayak, Shraban Kumar Sahoo, Pradip Kumar Prusty, Gagan Kumar Panigrahi "in silico molecular docking reveals the interaction of coumarin with the Sars-Cov-2 main protease". International Journal of Botany Studies, Vol 5, Issue 3, 2020, Pages 440-442
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