This article presents information on antioxidant activity, flavonoids, polysaccharides, amino acids and tannins of Gaillardia pulchella inflorescences. The aim of this work is to evaluate the chemical composition of the Gaillardia pulchella Foug inflorescences. The quantitative content of flavonoids and antacians was carried out by spectrophotometrical method. The content of pectin substances was determined by the M. Sinner method. Quantitative analysis of tannins was carried out permanganometrical method. The maximum content of the antioxidants was revealed in the 70% ethanolic extract of Gaillardia pulchella inflorescences. The content of water-soluble polysaccharides and pectin in the inflorescence Gaillardia pulchella meal is 4.5% and 5.1%, respectively. The sum of flavonoids in Gaillardia pulchella extract is 0.32 ± 0.01%. Based on the conducted qualitative reactions, condensed tannins are contained in the aqueous extract. In the water extract of Gaillardia pulchella inflorescences, aspartic and glutamic acids, α-alanine, α-proline, methionine and valine were found. Based on the obtained data, potassium predominates in the 70% ethanolic extract of Gaillardia pulchella inflorescences. In the result of this work, flavonoids, polysaccharides, amino acids, micro-, macroelements composition, and tannins of inflorescences Gaillardia pulchella were evaluated.