Radish (Raphanus sativus) and Citrus limon is consumed in India and considered as one of the major source of human diet. The major objective is to determine its antimicrobial and antioxidant activity of Radish (Raphanus sativus) especially its leaves and Citrus limon i.e. peel. In this study, phytochemical studies were conducted in order to analyze the presence of secondary metabolites and determined its antimicrobial (using three bacterial strains) and antioxidant (using DPPH, 2,2-diphenyl-1-picryl-hydrazyl-hydrate assay) activity. The results of these studies showed the existence of metabolites in different extracts and also showed its antimicrobial and antioxidant activity as well.