Objective: The plant Mimusops elengi is an annual or perennial ayurvedic plant, is widely distributed in India. It is used in traditional medicine, especially for skin disease, disease of the gum and teeth, astringent, diuretic, etc. Methods: The present paper report the macroscopically and microscopically studies of leaf of Mimusops elengi linn. Some distinct and different characters were observed with section of fresh leaf. Physiochemical parameter and preliminary phytochemical studies of the leaf powder were also carried out. Results: Anthelmintic activity of different extracts of leaves of Mimusops elengi Linn were investigated against Pheretima posthuma at various concentrations (10, 25, 50 mg/ml) of each extract were tested in the bioassay, which involved determination of time of paralysis and time of death of worms. Albendazole was included as standard reference and distilled water as control. The methanolic and ethyl acetate shows more potent anthelmintic activity. Conclusion: The present study on Pharmacognostical investigation of Mimusops elengi Linn. leaves might be useful to supplement information in regard to its identification parameters assumed significantly in the way of acceptability of herbal drugs in present scenario lacking regulatory laws to control quality of herbal drugs.