Moringa oleifera Lam commonly known as Moringa, a native plant from Africa and Asia, and the most widely cultivated species in Northwestern India, is the sole genus in the family Moringaceae. Several studies have demonstrated the beneficial effects in humans. MO has been recognized as containing a great number of bioactive compounds. The most used parts of the plant are the leaves, which are rich in vitamins, carotenoids, polyphenols, phenolic acids, flavonoids, alkaloids, glucosinolates, isothiocyanates, tannins and saponins. The present investigation was carried out to investigate anti-ulcer activity of various extract of the plant using indomethacin induced gastic ulcer.