In the folklore of Indian medicine, several herbs have been used traditionally as brain or nerve tonics. One of the most popular of these neurotonics is Brahmi (Bacopa monnieri), a well-known memory booster. Bacopa monnieri (family: Scrophulariaceae) is used in traditional medicine to treat various nervous disorders and as a Brain tonic for enhancing memory, intellect and to provide relief in anxiety or epileptic disorders. It is a small, creeping succulent herb. The leaf and flower bearing stems are 10-30 cm long and arise from creeping stems that form roots at the nodes with pale blue or pinkish white Flowers and grown nearly banks of freshwater streams and ponds, paddy fields, and other damp places. Traditionally in Unani system of medicine it has been used since long time to treat various diseases such as Epilepsy, Depression, anxiety, hysteria etc. Modern phytochemical evaluation of brahmi revealed that it contains brahmine, herpestine, bacoside A & B and saponins as the chief phytoconstituents. Bacoside A, B are the major constituents present in Brahmi plant in the form of saponins other than this D- mannitol, hersaponin and potassium salts are also present. Bacopa’s antioxidant properties may offer protection from free radical damage in cardiovascular disease. Neuropharmacological effect have been shown by isolated Bacoside and number of reports are available showing nootropic action.