The aim of this research was to estimate Terminalia chebula fruit anti-diabetic properties in Type 2 diabetic rats based on streptozotocin. Methanol extract of Terminalia chebula fruit significantly (p<0.05) decreased the level of fasting serum glucose. However, higher levels of liver glycogen and plasma insulin were seen in HFD / STZ controls relative to normal control animals and large increases of HbAlc rates at the end of the study. Besides Terminalia chebula hypoglycemic effect, a favorable effect was also found in the lipid profile. At the end of the study period, overall serum cholesterol and triglyceride were substantially reduced. The addition of TCF has substantially decreased in renal function markers (P<0.05) relative to the category HFD/STZ. Glibenclamide administration was also substantially decreased (p<0.01) in serum glucose levels. The experimental findings thus indicate that Terminalia chebula has hypolipidemic and hypoglycemic effects and may act as a source of strong antidiabetic drugs.