Medicinal plants are nature gift to human society to live disease free healthy life and is considered as a rich resource of constituents which can be used in drug development. Genus Erythrina belongs to the family Fabaceae. A wide range of chemical compounds have been isolated from it, mainly alkaloids, flavonoids and terpenoids and these bioactive compounds are responsible for the medicinal value. Plants have been investigated for various pharmacological actions i.e. antipyretic, anticancer, antiviral and anthelminthic. Almost each parts of the plants of this genus have been used in traditional medicine and have wide range of uses for the treatment of various diseases and disorders. It has been reported that bark of the plant is used maximum (42%) and roots are used minimum (4%) showed in Fig.2. The trend of plant part used as per medicinal values is Bark (42%) > Leaves (28%) > Flowers (16%) > Other plant parts (10%) > Roots (4%). The present review is therefore an effort to explore a detailed survey of the literature and current knowledge on its ethnomedicinal, phytochemical, therapeutic and pharmacological properties.