Industrialization is very fast growing during the human civilization. During this industrialization more pollutionis generated and due to the pollution, free radicals are generated. This free radical can damage the most of the cell of the animals and human. This may cause the various diseases in human and animal. Beside that there are various problems related to the inflammation. In search of the plants we find one of important plant Urginea indica (Roxb) which was one of the rare plant in the region of Maharashtra region as well as in India. We have obtained the plant from the Rajapur region of Maharashtra, India. The leaves are screened for the antioxidant activity by the DPPH, nitric oxide. Thisplant was studied for the phytochemical activity of the leaves and flowers. We also study the anti-inflammatory activity of the leaves by antioxidant and antiinflametry protocol. The result shows that the leaf of the plant shows the excellent antioxidant activity and the leaves and flowers contain various phytochemicals. The leaves extract shows the excellent anti-inflammatory activity. Urginea indica (Roxb) Kunth leaves shows the good antioxidant, anti-inflammatory activity.