Plant are important sources of drug additives, flavors and others. The importance of these secondary metabolites has resulted in the production of these products and their potential in recent years. Plants cell culture technologies have been introduced during the 1960's as a possible tool for both studying and producing plant secondary metabolites. The focus of the present is the application of tissue culture technology for the production of other important plant secondary metabolites. The present antimicrobial properties and importance of plant secondary metabolites.