Tinospora Cordifolia is a large, perennial, deciduous, climbing shrub of weak and fleshy stem which are found throughout India. The chemical constituents include alkaloids, glycosides, steroids, aliphatic compounds and polysaccharides. There are different potential medicinal properties include anti-diabetic, antipyretic, antispasmodic, anti-inflammatory, anti-arthritic, antioxidant, anti-allergic, anti-stress, anti-leprosy, antimalarial, hepatic-protective, immuno-modulatory and anti-neoplastic activities. This review analyze the various properties and medicinal uses of Tinospora cordifolia.