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VOL. 6, ISSUE 4 (2021)
Evaluation of anti-epileptic activity of Coriandrum sativum fruit extracts
Authors
Ankita Pant, Gaurav Saxena, Himanshi, Nutan, Pankaj Gill, Taljinder Kaur
Abstract
Epilepsy is a disease of the brain characterized by recurrent spontaneous seizures. All anti-epileptic drugs (AEDs) are of synthetic origin and known to present many side effects such as sedation, hepatotoxicity, anxiety, and depression. In our study, pentylenetetrazol (PTZ) kindling model of epilepsy was usedwith Sodium valproate as the standard. Anti-convulsive adequacy of fruit extracts of Coriandrum sativum (CAE and CHE) at a dose of 250mg /kg b.w and 500 mg/kg b.w. was evaluated. MDA levels in both cortical and hippocampal tissues of PTZ group were significantly higher than those of the control animals. C. sativum extracts had a significant effect on PTZ kindled mice.
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Pages:184-188
How to cite this article:
Ankita Pant, Gaurav Saxena, Himanshi, Nutan, Pankaj Gill, Taljinder Kaur "Evaluation of anti-epileptic activity of <em>Coriandrum sativum</em> fruit extracts ". International Journal of Botany Studies, Vol 6, Issue 4, 2021, Pages 184-188
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