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VOL. 6, ISSUE 4 (2021)
A current review on natural binders used in pharmaceuticals
Authors
S Gunasekaran, Sutharsan T
Abstract
Binders are applied to tablet formulations to give them plasticity and thus increase the strength of inter-particle bonding inside the tablet. The research and production of new excipients for use as a binding agent in tablet formulations is still a hot subject. This is due to the fact that different binding agents can be used to achieve different tablet mechanical strengths and drug release properties for various pharmaceutical purposes. Binders are substances that give granules their cohesiveness. The composition of granules of derived hardness and size ensures that the tablet remains intact after compression while also enhancing the flow qualities. Natural binders including starch, gums, mucilage, and dried fruits have binding properties as well as filler and disintegrant properties. Natural polymers are safe and economical than synthetic polymers like PVP. Natural gums and mucilage are naturally occurring plant components that are relatively inexpensive and abundant. They are commonly used as natural excipients in both traditional and novel dosage types, and they have the potential to be biodegradable polymeric Materials. With the growing interest in natural-source polymers, the pharmaceutical industry has decided to use the majority of them in formulations. Natural products have grown in popularity in recent years, and they are now widely used for a number of purposes. Excipients were used as inert vehicles in drug formulations to provide the required weight, consistency, and volume for the proper administration of the active ingredient, but in modern pharmaceutical dosage forms they often fulfill multi-functional roles such as modifying release, enhancement of the active ingredient's stability and bioavailability must be improved, as well as patient acceptability and manufacturing simplicity.
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Pages:800-806
How to cite this article:
S Gunasekaran, Sutharsan T "A current review on natural binders used in pharmaceuticals ". International Journal of Botany Studies, Vol 6, Issue 4, 2021, Pages 800-806
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