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VOL. 6, ISSUE 4 (2021)
Effect of flavonoid rich fraction from the leaves of Clinacanthus nutans on antiradical and anti-inflammatory properties
Authors
S Tamilselvi M D
Abstract
To evaluate the antioxidant and anti-inflammatory activities of flavonoid rich fraction from the leaves of Clinacanthus nutans. In this framework, the in vitro antioxidant activity was demonstrated by ABTS radicals, reducing power, lipid peroxidation, nitric oxide scavenging activities and anti-inflammatory activity was evaluated first by studying inhibiting the denaturation of albumin and inhibition of lipoxygenase activities. Total phenolic and flavonoid content were found respectively (78.32 ± 2.45) mg gallic acid equivalent/g, and (43.21 ± 2.78) mg quercetin equivalent/g. The extract displayed significant scavenging activity of some radicals such as ABTS EC50 value 65.31µl/ml at 100 µl/ml. Flavonoid rich fraction from the leaves of C. nutans showed in vitro anti-inflammatory activity by inhibiting albumin denaturation EC50 value 69.32 µl/ml and inhibition of lipoxygenase EC50 value 83.65 µl/ml. Our results show that Flavonoid rich fraction from the leaves of C. nutans has good antioxidant activity and interesting anti-inflammatory properties. Flavonoid rich fraction from the leaves of C. nutans extract can be used to prevent oxidative and inflammatory processes.
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Pages:606-610
How to cite this article:
S Tamilselvi M D "Effect of flavonoid rich fraction from the leaves of <em>Clinacanthus nutans</em> on antiradical and anti-inflammatory properties ". International Journal of Botany Studies, Vol 6, Issue 4, 2021, Pages 606-610
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