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VOL. 6, ISSUE 4 (2021)
An In vitro study on anti-diabetic and antiradical activities of siddha medicine avarai kudiner chooranam
Authors
G Swetha Lakshmi, P Bama, S Mathukumar
Abstract
Plants offer us bioactive molecules those may serve as safer therapeutics to combat existing new world ageing related diseases, and diabetic is the major concern among them. Pancreatic lipase inhibitors from plant sources may prove as promising side effects lacking anti-diabetic therapeutics, present study was conceived with the objective of anti-lipase, antiradical activities of Avarai kudiner chooranam decoction. Phytochemical constituents were screened quantifications of total phenolics, tannins, flavonoids, were done by taking tannic acid, quercetin, as reference molecules. Antiradical activities were evaluated by using two different free radicals (ABTS and lipid peroxidation activities). The antiradical activity of Avarai kudiner chooranam decoction was proved to be better than the standard ascorbic acid. Antidiabetic function of Avarai kudiner chooranam decoction was assessed using amylase and glucosidase in an in vitro assay system. From the data of the results obtained, maximum percentage of amylase inhibition was shown by Avarai kudiner chooranam decoction (78.32 %) than standard drug. EC50 value were calculated using the logarithmic regression of the dose-response curve after subtraction of both blank and inherent sample fluorescence values. In all cases, the coefficients of determination of the regression (R2) were greater than 0.95. EC50 are the means ± standard deviations of three determinations.
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Pages:891-895
How to cite this article:
G Swetha Lakshmi, P Bama, S Mathukumar "An <em>In vitro</em> study on anti-diabetic and antiradical activities of siddha medicine avarai kudiner chooranam ". International Journal of Botany Studies, Vol 6, Issue 4, 2021, Pages 891-895
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