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VOL. 6, ISSUE 4 (2021)
An invtro study on anti-obesity and antiradical activities of siddha medicine seenthil chooranam
Authors
N R Panneerselvam
Abstract
Traditional systems of medicine have been in trend for treating numerous ailments in many develop and development countries such as India, China, Japan and Korea, Tavian since age-old time. Siddha system of medicine is one of the ancient traditional system of India and practiced mostly in its southern part of India for treating different diseases including even chronic conditions. Seen thil chooranam composed of purified Tinospora cardifolia. Pancreatic lipase inhibitors from plant sources may prove as promising side effects lacking anti-obesity therapeutics, present study was conceived with the objective of anti-lipase, antiradical activities of seenthil chooranam decoction. Phytochemical constituents were screened quantifications of total phenolics, tannins, flavonoids, were done by taking tannic acid, quercetin, as reference molecules. Antiradical activities were evaluated by using different free radicals (ABTS, lipid peroxidation, metal chelating, superoxide and nitric oxide scavenging activities). The antiradical activity of seenthil chooranam decoction was proved to be better than the standard ascorbic acid. Antilipolytic function of seenthil chooranamdecoction was assessed using porcine pancreatic lipase (PPL; triacylglycerol lipase, EC 3.1.1.3) in an in vitro assay system with p-nitrophenyl palmitate (p-NPP) as a substrate. From the data of the results obtained, maximum percentage of lipase inhibition was shown by seenthil chooranam decoction (82.3%) than standard drug. In all cases, the coefficients of determination of the regression (R2) were greater than 0.95. IC50 are the means ± standard deviations of three determinations.
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Pages:983-987
How to cite this article:
N R Panneerselvam "An invtro study on anti-obesity and antiradical activities of siddha medicine seenthil chooranam ". International Journal of Botany Studies, Vol 6, Issue 4, 2021, Pages 983-987
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