ARCHIVES
VOL. 6, ISSUE 5 (2021)
Formulation and evaluation of antiinflammatory gel from the leaves extract of Acalypha indica
Authors
S Gunasekaran, V Muruganantham, G R Vijaasankar, K Somu
Abstract
Topical application of gel at pathological sites offer great advantage in a faster release of drug directly to site of action, independent of water solubility of the drug as compared to cream and ointments. Some of these systems are as clear as water in appearance, visually aesthetically pleasing as in gelatin deserts and other are turbid. The clarity range from clear to a whitish translucent. The polymer are used between 0. 5 – 15% and in most of the cases they are usually at the concentration between 05 -2%. Gels are usually clear transparent semisolid containing the solubilized active substances. Thus facts have clearly indicated that a formulation and development of a gel based topical dosage from Anti-inflammatory drug will be proved to be worth life. Hence a study on formulation and evaluation of gels for a new antibacterial drug Acalypha indica was selected as The principle object of this work. The main aim of the present study was to formulate and evaluate a natural anti-inflammatory gel by using different polymers. The Acalypha indica gel formulation was optimized on the basic of different physical parameters. Studies mainly carried out for pH, viscosity, Spreadability, Extrudability, in vitro and stability studies. Various formulation of Acalypha indica leaves extract gels were formulated by using various polymers such as CMC Na, HPMC K100, HPMC K4M, and Carbomer 940. Thus by the addition of suitable neutralizing agents both formulations are made more elegant and applicable for skin pH.
Download
Pages:772-777
How to cite this article:
S Gunasekaran, V Muruganantham, G R Vijaasankar, K Somu "Formulation and evaluation of antiinflammatory gel from the leaves extract of <em>Acalypha indica</em> ". International Journal of Botany Studies, Vol 6, Issue 5, 2021, Pages 772-777
Download Author Certificate
Please enter the email address corresponding to this article submission to download your certificate.