2019 Novel corona-virus (2019-nCoV) also referred to as severe acute respiratory syndrome Corona-virus 2 (SARS-CoV-2) has put the entire globe into turbulence. Unavailability of specific drug against the virus is more essential. This demanding situation requires development of bio-molecules for efficient treatment against severe acute SARS-CoV-2. The crystal structure of SARS-CoV-2 main protease (M^pro) can be used for fast in silico molecular docking. This may result into identification of pharmacophores including phytochemical. In silico molecular docking revealed that the phytochemical, epicatechin effectively binds to the active pocket of the SARS-CoV-2 main protease.